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Jacob Syndrome

What is Jacob's Syndrome?

Jacob's syndrome is a rare chromosomal disorder that affects males. It is caused by the presence of an extra Y chromosome. Males normally have one X and one Y chromosome. However, individuals with Jacob's syndrome have one X and two Y chromosome.

Males with Jacob's syndrome, also called XYY males.

What causes Jacob's syndrome?

Jacob's syndrome occurs when a male inherits two Y chromosomes from his father instead of one. He is an XYY male. Most males are XY.

The exact cause of the XYY aberration is unknown.

What are all the symptoms of Jacob's syndrome?

There are many symptoms associated with Jacob's Syndrome. The most common symptoms are:

  • learning problems at school
  • delayed emotional maturity

What are the Physical Characteristics of Jacob's Syndrome?

Males with Jacob’s syndrome are tall, thin, have acne, speech problems, and reading problems.

Complications Jacob's Syndrome

Males with XYY have no increased risk of developing additional diseases. In rare cases males with Jacob's Syndrome will also have Klinefelter's syndrome.

Males with Jacob's Syndrome will have a normal sexual libido and potency.

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